Our expertise
We are expert problem solvers in data curation, image and video annotation, connectomics and more.
Our scientists work with you to understand your priorities and help you make sense of your dataset. We adapt to your platform of choice and work with a wide range of imaging modalities, including volume electron microscopy, light-level volumetric datasets, x-ray holotomography, expansion microscopy, multiphoton and confocal laser scanning microscopy, time series and video data.
Our services are individually tailored to your project goals, whether you need ground truthing and reconstruction, proofreading specific cells, cell typing and matching, behavioural analysis, quantification, or a more custom service.
Ground truthing
Setting the ground truth for cutting-edge research.
We help you establish the scope and scale of your initial analysis approach. We identify challenges, assess the suitability of your dataset for specific analyses, and provide robust, detailed annotations which underpin reliable data interpretation.
We also work with your data in the later stages as your project develops. We tackle problem areas, verify accuracy and help you to continually fine-tune your approach.
Histology, volumetric data and connectomics:
Cell skeletonisations and 3D segmentation
Detailed manual reconstruction of fine processes and small structures
Annotating synapses and subcellular structures
Region of interest quantification
Bridging artefacts, missing regions and lateral shifts
Data quality assessment for pre-computational stages
Time series and video data annotation:
Event detection and timestamping
Animal behaviour and clinical tracking
Ground truth for machine learning
Proofreading
Giving you confidence in your dataset.
We provide comprehensive proofreading services for all types of image and video data, so that you can perform your analyses with confidence. We approach both manual and automated image segmentations with an expert eye for detail, working on broad quality checks or intricate refinements.
Our experienced and efficient proofreaders work to your specific requirements for data annotations, level of detail and speed, ensuring that your dataset is accurate and reliable.
Histology, volumetric data and connectomics :
Quality checks and counts for specific cells or areas of interest
Coarse proofreading of overall morphology, backbone structure and/or major structures
Fine-detail proofreading of complete cells, processes, synaptic terminals and more
Fixing problem areas, artefacts and path swaps
Proofreading automated predictions:
Region of interest verification
Synapse, organelle and subcellular structure verification
Proofreading quality assessment for machine learning
Identification and classification
Understanding your data as a whole.
When you’re immersed in big data, we can help you explore the biology. Our expert team can help with a wide variety of identification and classification tasks, from assigning cell types to categorising behaviours.
Our thorough and systematic annotations help you see the big picture within your data, all while understanding its constituent elements in depth. We can provide identification and classification services either as a standalone project, or alongside ground truthing and proofreading.
Histology, volumetric data and connectomics:
Atlas and resource-based region of interest classification
Cell type annotation and matching for cell classes, sub-classes and types
Synapse, subcellular structure and organelle type classification
Manual and semi-automated seeding for tracts, hemilineages and more
Video data and automated analyses:
Animal behaviour classification
Score assignment for automated matches
Inter-dataset and cross-dataset comparisons
“Aelysia has supported our connectomics projects over the past couple years, and we could not be happier with their work. Their team is dynamic and highly flexible, working efficiently across diverse datasets and platforms. I would highly recommend Aelysia to anyone seeking reliable, technically skilled partners in large-scale neuroscience and connectomics projects.”
Learn with us
At Aelysia, we develop research through long-term collaborations. We work closely with your team to understand and advance your project together, but we know that sometimes, passing down technical knowledge to new team members can be challenging.
We provide training services to our partner labs in academia and industry, so that your team can develop their skills while your project moves forward. If you need help in training new lab members, bringing people on board or simply brushing up your own knowledge, just get in touch. We also offer bespoke scientific writing and editing services.
Contact us
We’re always excited to hear about new scientific projects. Contact us here and our team will get back to you soon.
